Realising TERRANOVA’s ambitious and long-term vision requires a concrete scientific methodology combined with a well-established work plan. In what follows, we describe how and by which means we will achieve the project objectives and consolidate them towards the envisaged system concept. TERRANOVA’s work plan is organised around five key interacting Work Packages (WPs), complemented by the necessary project management and dissemination, exploitation and communication activities performed under the first (WP1) and the last (WP7) Work Package, respectively.